Genus Rubiaceae

Common Names

Indian Mulberry (India), Noni (Hawaii), Nono (Tahiti and Raratonga), Polynesian Bush Fruit, Painkiller Tree (Caribbean islands), Lada (Guam), Mengkudo (Malaysia), Nhau (Southeast Asia), Grand Morinda (Vietnam), Cheesefruit (Australia), Kura (Fiji), Bumbo (Africa) Note: This is only a small sampling of vernacular names for Morinda citrifolia. Almost every island nation of the South Pacific and Caribbean has a term for this particular plant . This booklet will refer to the herb mainly as “ noni” or M. citrifolia, and is referring primarily to Hawaiin noni.

Parts Used

The parts of the noni plant most used for their medicinal and nutritional purposes are the fruit, seeds, bark, leaves, and flowers. Virtually every part of the noni plant is utilized for its individual medicinal properties; however, it is the fruit portion that is regarded as its most valuable. The seeds have a purgative action, the leaves are used to treat external inflammations and relieve pain, the bark has strong astringent properties and can treat malaria, the root extracts lower blood pressure, the flower essences relieve eye inflammations and the f ruit has a number of medicinal actions.

Physical Description

Morinda citrifolia is technically an evergreen shrub or bush, which can grow to heights of fifteen to twenty feet . It has rigid, coarse branches which bear dark, oval, glossy leaves. Small white fragrant flowers bloom out of cluster-like pods which bear creamy-white colored fruit. The fruit is fleshy and gel-like when ripened, resembling a small breadf ruit . The flesh of the fruit is characterist ically bitter, and when completely ripe produces a rancid and very dist inctive odor. Noni has buoyant seeds that can float formont hs in ocean bodies. The wood of the inflammatory, astringent, emollient, emmenagogue, laxative, sedative, hypotensive (lowers blood pressure) , blood purif ier, and tonic.

Chemical Constituents

Noni has various chemical constituents. First, it has an impressive array of terpene compounds, three of which—L. Asperuloside, aucubin, and glucose— have been identified by their actyl derivatives. Both caproic and caprylic acids have been isolated.1 Second, bushfruits, a category of which noni fruit is a member, are also considered a good source of vit - amin C.2 Third, Hawaiin noni has been linked to the synthesis of xeronine in the body which has significant and widespread health implications. Last , the alkaloid cont ent of the noni fruit is thought to be responsible for its therapeutic actions. Alkaloids exhibit a wide range of pharmacological and biological act ivitiesin the human body. They are nitrogencontaining organic compounds which can react with acids to form salts and which are the basis of many medicines. The following is an in-depth chemical analysis of each plant part and it s chemical constituents.

FLOWER

FRUIT

discovered an alkaloid in the Hawaiin noni fruit which he calls proxeronine and which he believes has appreciable physiological actions by acting as a precursor to xeronine, a very crucial compound (see later sections) . In addition, a compound found in the fruit called damnacanthol is believed to help inhibit cert ain viruses and cellular mutations involved in cancer.

ROOT AND ROOT BARK

Pharmacology

Recent surveys have suggested that noni fruit exerts antibiotic action. In fact, a variety of compounds which have antibacterial properties (such as aucubin) have been identified in the fruit.5 The 6-Dglucopyranose pentaacet ate of the fruit extract is not considered bacteriostatic.6 Constituents found in the fruit portion have exhibited ant imicrobial action against Escherichia coli, Salmonella typhi (and other types) , Shigella paradysenteriae, and Staphylococcus aureaus. Compounds found in the root have the ability to reduce swollen mucous membrane and lower blood pressure in animal studies. Proxeronine is an alkaloid constituent found in Hawaiin noni fruit which may prompt the production of xeronine in the body. It is considered a xeronine precursor and was discovered in noni fruit by Dr. Ralph M. Heinicke. He has theorized that this proenzyme can be effective in initiating a series of beneficial cellular reactions through its involvement with the integrity of specific proteins. He points out that tissues contain cells which possess certain recept or sites for xeronine. Because the reactions that can occur are so varied, many different therapeutic actions can result when xeronine production escalates, explaining why Hawaiin noni is good for so many seemingly unrelated disorders. Damnacanthol is another compound contained in the fruit of the Hawaiin noni plant which has shown the ability to block or inhibit the cellular function of RAS cells, considered pre-cancerous cells.

Body Systems Targeted

The following body systems have all been effec-freeze-dried capsules, dehydrated powder or fruit, and oil. Noni plant constituents are sometimes offered in combination with other herbs. Some products contain a percent age of the fruit, bark, root and seeds for their individual therapeutic properties.

Satety

Extracts of M. citrifolia are considered safe if used as directed; however, pregnant or nursing mothers should consult their physicians before taking any supplement . High doses of root extracts may cause constipation. Taking noni supplements with coffee, alcohol or nicotine is not recommended.

Suggested Uses

Ideally, noni extracts should be taken on an empty stomach prior to meals. The process of digesting food can interfere with the medicinal value of the alkaloid compounds found in Hawaiin noni, especially in its fruit . Apparently, stomach acids and enzymes destroy the specific enzyme which frees up the xeronine compound. Take noni supplements without food, coffee, nicotine or alcohol. Using supplements that have been made from the semi-ripe or light - green fruit is also considered preferable to the ripe, whit ish fruit .

NONI: ITS USE AND HISTORY

Noni is a tropical wandering plant indigenous to areas of Australia, Malaysia and Polynesia. It is considered native to Southeast Asia although it grows from India to the eastern region of Polynesia. Morinda citrifolia has a long history of medicinal use throughout these areas. It is thought to be the “most widely and commonly used medicinal plant prior to the European era.” 7 Centuries ago, the bushfruit was introduced to native Hawaiians, who subsequently called it “noni” and considered its fruit and root as prized medicinal agents. Among all Polynesian botanical agents of the 19th and 20th centuries, Hawaiin noni has the widest array of medical applications. Samoan and Hawaiian medical practitioners used noni for bowel disorders (especially infant diarrhea, constipation, or intestinal parasites) , indigestion, skin inflammation, infection, mouth sores, fever, contusions and sprains. Hawaiians commonly prepared noni tonics designed to treat diabetes, stings, burns and fish poisoning.8 The herb’s remarkable ability to purge the intestinal tract and promote colon health was well known among older Hawaiian and Tahitian natives and folk healers. Interestingly, field observations regarding its repu-remarkable healing agent .

Wonder Herb of Island Folk Healers

Common to t he thickets and forests of Malaysia and Polynesia, and the low hilly regions of the Philippine islands, noni has been cultivated throughout communities in the South Pacific for hundreds of years. Its Hawaiian use is thought to originate from inter-island canoe travel and settlement dating to before Christ . Its hardy seeds have the ability to float which has also contributed to its distribution among various seacoasts in the South Pacific region. Historical investigation has established the fact that some of Hawaii’s earliest settlers probably came viaTahiti. For this reason, Tahitian herbal practices have specific bearing on the herbal therapeutics of islands to the nort h. The very obvious similarities between the Hawaiian vernacular for herbal plants like noni and Tahitian names strongly suggests the theory of Polynesian migrations to Hawaii. Cultures native to these regions favored using Morinda citrifolia for treating major diseases and ut ilized it as a source of nourishment in times of famine.9 Noni fruit has been recognized for centuries as an excellent source of nutrition. The peoples of Fiji, Samoa and Rarat onga use the fruit in both its raw and cooked forms.10 Traditionally, the fruit was propicked before it was fully ripe and placed in the sunlight . After being allowed to ripen, it was typically mashed and its juice extracted through a cloth. Noni leaves provided a veget able dish and their resiliency made them desirable as a fish wrap for cooking.

Noni’s Medical Reputation

Elaborate traditionalrituals and praying rites usually accompanied the administration of noni. Int erestingly, cultures indigenous to the Polynesian islands had a significant understanding of their flora. For example, native Hawaiians maint ained a folkmedicine taxonomy t hat was considered second to none.11 Noni was not only used for medicinal purposes but for its food value, for clot hing and for cloth dyes as well. Research indicates that noni was among the few herbal remedies that islanders considered “ tried and true.” In Hawaii, trained herbal practitioners reserved the right to prescribe plant therapies.12 Records indicate that Hawaiian medical practices were based on extensive and very meticulous descriptions of symptoms and their prescribed herbal treatments. Dosages were controlled and the collection and administration of plant extracts was carefully monitored.13 In addition to Morinda, it was not uncommon for these herbal doctors to also recommend using In regard to its application for common ailments, Hawaiians and other island communities traditionally prescribed noni to purge the bowel, reduce fever, cure respiratory infections such as asthma, ease skin inflammations, and heal bruises and sprains. In other words, noni was widely used and highly regarded as a botanical medicine.

A Timely Reemer gence

Today, the natural pharmaceutical actions of the chemical constituents contained in noni are scientif-ically emerging as valuable bot anical medicines. Tahitian “nono” intrigued medical practitioners decades ago; however, due to the eventual emergence of synthetic drugs, interest in this island botanical diminished until recent years. Ethnobot anists are once again rediscovering why Hawaiian people havet reasured and cultivat ed Morinda citrifolia for generations. Noni is now finding its way into western therapeutics and is referred to as “ the queen” of the genus Rubiaceae. Its ability to reduce joint inflammation and target the immune system have made it the focus of the modern scientific inquiry. Dr. Ralph Heinicke has conducted some fascinating studies on the chemical constituents of the Hawaiin noni fruit. His research centers on the proxeronine content of the fruit juice and how it profoundly influences human physiology. In addition, scientific studies investigating noni as an anti-cancer agent have been encouraging. It s conspicuous attributes and varied uses have elevat edits status to one of the best of the healing herbs. Today Morinda citrifolia is available in liquid, juice, freezedried capsules, or oil forms, and is considered one of nature’s most precious botanicals.

TRADITIONAL USES OF NONI

Throughout tropical regions, virtually every part of Morinda citrifolia was used to treat disease or injury. Its curative properties were well known and commonly employed. PatoaTama Benioni, a member of the Maoritribe from the Cook Islands and a lecturer on island plants explains: Traditionally Polynesians use noni for basically everything in the treatment of illness. Noni is a part of our lives. Any Polynesian boy will tell you he’s had exper ience with it . We use juice from its roots, its flowers, and its fruit... my grandmother taught me to use noni from the roots and the leaves to make medicine for external as well as internal use, and for all kinds of ailments, such as coughs, boils, diseases of the skin, and cuts.15

decoctions to stimulate delayed menst ruation.

XERONINE: THE SECRET OF NONI?

One informed professional on the subject of noni is Dr. Ralph Heinicke, a biochemist who has researched the active compounds of noni fruit for a number of years. He discovered that the Hawaiin noni fruit contains an alkaloid precursor to a very vital compound called xeronine. Wit hout xeronine, life would cease. In Dr. Heinicke’s view, noni fruit provides a safe and effective way to increase xeronine levels, which exert a crucial influence on cell health and protction. His research suggests that the juice from the M. citrifolia fruit contains what could technically be considered a precursor of xeronine—proxeronine. This compound initiates the release of xeronine in the intestinal tract after it comes in contact with a specific enzyme which is also contained in the fruit .

Because proteins and enzymes have so many varied roles within cell processes, the normalization of these proteins with noni supplemenation could initiate avery wide variety of body responses and treat many disease condit ions. Proteins are the most important catalysts found in the body. The beauty of obtaining a precursor to xeronine from the noni fruit is that the body naturally decides how much of this precursor to convert to xeronine. Disease, stress, anger, trauma and injury can lower xeronine levels in the body, thus creat ing a xeronine deficit . Supplementing the body with noni fruit is considered an excellent way to safely and naturally raise xeronine levels. It is the research and theories of Dr. Heinicke which have made the juice of the Hawaiin noni fruit a viable medicinal substance. He writes: Xeronine is analkaloid, a substance the body produces in order to activate enzymes so they can function properly. It also energizes and regulates the body. This par-ticular alkaloid has never been found because the body makes it, immediately uses it, and then breaks it down. At no time is there an appreciable, isolable amount in the blood. But xeronine is so basic to the functioning of proteins, we would die without it . Its absence can cause many kinds of illness.17 Because so many diseases result from an enzyme malfunction, Dr. Heinicke believes that using the noni fruit can result in an impressive array of curative applications. Interestingly, he believes that we manufacture proxeronine while we are sleeping. He proposes t hat if we could constantly supply our bodies wit h proxeronine from other sources, our need to sleep would diminish.18

NONI PROCESSING

How an herb is processed is crucial to how beneficial it is: this is especially true of noni, with its unique enzymes and alkaloids. Morinda citrifolia should be picked when the fruit is turning from its dark green immature color to its lighter green color, and certainly before it ripens to its white, almost translucent color. Once picked, noni, like aloe, will denature extremely quickly due to its very active enzymes. After harvesting, it should swiftly be flash frozen. This is similar to what is done to fish caught at sea to keep them f esh. This stops it from losing its potency while not damaging any of its constituents. To process noni, freeze-drying is recommended. This removes only the water without damaging any of this miracle plant’s vital enzymes and other phytonutrients like xeronine and proxeronine. This pure high-quality noni fruit juice powder is then encapsu-has a very harsh taste and an extremely foul smell, similar to the fruit it self . Other methods of processing include thermal processing, dehydrat ion and air drying. Thermal processing is generally found in liquids, while the dehydrat ed noni is then milled and encapsulated. Unfortunately both methods utilize high heat (110+°F) , which can deactivate many of the vital compounds that make noni so import ant . Air-drying is effect ive without using damaging heat but has serious quality control problems for commercial production.

MODERN APPLICATIONS OF NONI

Overview

Noni possesses a wide variety of medicinal properties which originat e from its differing plant component s. The fruit and leaves of the shrub exert antibacterial activities. Its roots promote the expulsion of mucus and the shrinkage of swollen membranes making it an ideal therapeutic for nasal congest ion, lung infect ions, and hemorrhoids. Noni root compounds have also shown natural sedative properties as well as the ability to lower blood pressure.

Leaf extracts are able to inhibit excessive blood flow or to inhibit the formation of blood clots. Noni is particularly useful for its ability to treat painful joint conditions and to resolve skin inflammations. Many people drink noni fruit extracts in juice form for hypert ension, painful menstruation, arthritis, gastric ulcers, diabetes, and depression. Recent studies suggest that its anticancer activit y should also be considered. Concerning the therapeutic potential of the Hawaiin noni fruit, Dr. Heinicke writes: I have seen the compound found in noni work wonders. When I was still investigating its possibilities, I had a friend who was a medical research scientist administer the proxeronine to a woman who had been comatose for three months. Two hour safter receiving the compound, she sat up in bed and asked where she was. . . . Noni is probably the best source of proxeronine that we have today.19 Studies and surveys combined support the ability of noni to act as an immunost imulant, inhibit the growth of certain tumors, enhance and normalize cellular function and boost tissue regeneration. It is considered a powerful blood purifier and contributor to overall homeostasis.

xeronine, which appears to be able to regulate the shape and integrity of cert in proteins that individually contribute to specific cellular activities. Interestingly, this effect seems to occur after ingestion, inferring that the most active compound of noni may not be present in uneaten forms of the fruit or other plant parts. Some practitioners believe that xeronine is best obtained from a noni fruit juice precursor compound. The enzymatic reactions that occur with taking the juice on an empty stomach are what Dr. Heinicke believes set cellular repair intomotion.

Cancer

A study conducted in 1994 cited the anticancer activity of Morinda citrifolia against lung cancer. A team of scientists from the University of Hawaii used live laboratory mice to test the medicinal properties of the fruit against Lewis lung carcinomas which were artificially transferred to lung tissue. The mice that were left untreated died in nine to twelve days. However, giving noni juice in consistent daily doses significantly prolonged their life span. Almost half of these mice lived for more than fifty days.20 Research conclusions state that the chemical constituents of the juice acted indirectly by enhancing the ability of the immune system to deal with the invading malig-nancy by boosting macrophage or lymphocyte activit y. Furt her evaluation theorizes that the unique chemical constituents of Morinda citrifolia initiate enhanced T-cell activity, a reaction that may explain noni’s ability to treat a variety of infectious diseases. 21

In Japan, similar studies on tropical plant extracts found that damnacanthol, a compound found in Morinda citrifolia, is able to inhibit the function of KRAS- NRK cells, which are considered precursors to certain types of malignancies.22 The experiment involved adding noni plant extract to RAS cells and incubating them for a number of days. Observation disclosed that noni was able to significantly inhibit RAS cellular function. Among 500 plant extracts, Morinda citrifolia was determined to contain the most effective compounds against RAS cells. Its damnacanthol content was clinically described in 1993 as “a new inhibit or of RAS function.” 2 3 The xeronine fact or is also involved in that xeronine helps to normalize the way malignant cells behave. While they are still technically cancer cells, they no longer function as cells with unchecked growth. In time, the body’s immune system may be able to eradicate these cells.

Arthritis

with arthritic disease. One link to arthritic pain may be the inability to properly or completely digest proteins which can then form crystal-like deposits in the joints. The ability of noni fruit to enhance protein digestion through enhanced enzymatic function may help to eliminate this particular phenomenon. In addition, the alkaloid compounds and plant met abolites of noni may be linked to its apparent anti-inflammatory action. Plant sterols can assist in inhibiting the inflammatory response which causes swelling and pain. In addition, the antioxidant effect of noni may help to decrease free radical damage in joint cells, which can exacerbate discomfort and degeneration.

Immune System

The alkaloid and other chemical compounds found in noni have proven themselves to effectively control or kill over six types of infectious bacterial strains including: Escherichia coli, salmonellatyphi (and other types) , shigella paradysenteriae, and staphylo - coccus aureaus.25 In addition, damnacanthol, was able to inhibitt he early antigen stage of the Epstein- Barr virus.

The bioactive components of the whole plant, combined or in separate portions, have demonst rat - ed the ability to inhibit several different strains of bacteria. Anecdotal reports support this action in that noni seems particularly effective in shortening the duration of certain types of infection. This may explain why noni is commonly used to treat colds and flu. The chemical constituents found in noni and the possibility that they stimulate xeronine production— as well as initiate alkaloid therapy—may explain noni’s reputation for having immuno-stimulatory properties. Alkaloids have been able to boost phagocytosis which is the process in which certain white blood cells called macrophages attack and literally digest infectious organisms. Interestingly, the ant it umoraction of noni has been ascribed to an immune system response which involves stimulating T-cells. tropical regions during World War II learned of the fruit’s ability to boost endurance and stamina. Native cultures in Samoa, Tahiti, Raratonga and Australia used the fruit in cooked and raw forms. M. citrifolia is considered a tonic and is especially recommended for debilitated conditions.

Antioxidant

The process of aging bombards the body with free radicals which can cause all kinds of degenerative diseases. The xeronine theory promoted by Dr. Heinicke submit s t hat as our bodies age, we lose our ability to synthesize xeronine. To make matters worse, the presence of many environment altoxins actually blocks the production of xeronine as well. He believes that the proxeronine content of Hawaiin noni fruit juice can help to block these actions, thereby working as an antiaging compound.26 The phytonutrients found in noni assist in promot - ing cell nourishment and prot ect ion from free radicals created by exposure to pollution and other potentially damaging agents. In addition, Morinda citrifolia contains selenium, which is considered one of the best antioxidant compounds available.

Diabetes

While scientific studies are lacking in this particular application of noni, Hawaiians used various parts of the plant and its fruit to treat blood sugar disorders. Anecdotal surveys have found t hat noni is current ly recommended for anyone with diabetes.

Pain Killer

A 1990 study found that extracts derived from the Morinda citrifolia root have the ability to kill pain in animal experiments.27 Interest ingly, it was during this study that the natural sedative action of the root was also noted. This study involved a French team of scientists who noted a significant central analgesic activity in laboratory mice.28 Dr. Heinicke has stated, “Xeronine also acts as a pain reliever. A man wit h very advanced int est inal cancer was given three months to live. He began taking the proxeronine and lived for a whole year, pain-free.” 29

Skin Healing Agent

One of the most prevalent hist rical uses of noni was in poultice form for cuts, wounds, abrasions, burns and bruises. Using its fruit extract for very serious burns has resulted in some extraordinary healing. Because skin is comprised of protein, it immediately responds to the presence of xeronine.

burn site throught he direct application of a noni poultice is considered quite effective by Dr. Heinicke and his colleagues, who have studied enzymatic therapy. Concerning burns, he has written: I believe that each tissue has cells which contain proteins which have receptor sites for the absorption of xeronine. Certain of these proteins are the inert for ms of enzymes which require absorbed xeronine to become active. This xeronine, by converting the body’s procol- langenase system into a specific protease, quickly and safely removes the dead tissue from burns.30

Drug Addiction

The xeronine link to treat ing drug addiction is based on the notion that flooding t he brain with extra xeronine can reverse the neurochemical basis for addiction. This natural alkaloid is thought to normalize brain receptors which subsequent ly results in the cessation of physiological dependence on a certain chemical like nicotine.3 1 The potential of Hawaiin noni as a natural stimulat or for t he production of xeronine may have profound implications in treating various types of addictions.

Complementary Agents of Noni

PrimaryApplications of Noni

--
Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=570)

Date: June 29, 2005 09:44 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: SYTRINOL - For Heart Health, Don’t Be Confused About Cholesterol...

SYTRINOL - For Heart Health, Don’t Be Confused About Cholesterol...

Maintaining your cardiovascular health is one of the best ways you can stay fit. That means working to keep your cholesterol levels within the normal range. And contrary to popular belief, the amount of cholesterol you consume in food is not the most important factor for regulating normal cholesterol levels. It is actually the liver’s imbalanced production of cholesterol that is much more critical for your cardiovascular health.

You can address the root cause of maintaining normal cholesterol levels today with Source Naturals SYTRINOL™. This patented blend of citrus polymethoxylated flavones and tocotrienols has been clinically shown to promote cardiovascular health by supporting normal cholesterol production by your liver, promoting balanced triglyceride (fat) production, and providing antioxidant protection. Source Naturals, an industry leader in many categories, introduces the science of SYTRINOL™ in the CHOLESTEROL RESCUE™ product family to support your better heart health today.

The Truth About Cholesterol

Cholesterol is a very confusing subject – our bodies require it but we can also get too much of it. Cholesterol is one type of the ring-shaped compounds called sterols. Other sterols include bile acids, sex hormones, adrenal hormones and vitamin D. Approximately 90% of the cholesterol in your body is in your cell membranes. The remaining 10% can be found in your blood and throughout your body.

Liver’s Over-Production of Cholesterol

When your body needs more cholesterol, your liver takes carbohydrates, proteins and fats (also called triglycerides) from your diet and converts them into cholesterol. The amount of cholesterol that you might consume from foods (in animal products such as eggs, milk, cheese and beef ) is minute compared to the amount of cholesterol produced by your liver. Thus, cholesterol from food isn’t as critical to your total cholesterol. But balancing the cholesterol produced by your liver is very critical to your total cholesterol and thus, your cardiovascular health.

Oxidized LDL Cholesterol

Despite the confusion, cholesterol is a vital component of good health that strengthens cell membranes and provides building blocks for hormones, bile and vitamin D production. However, there is one potential pathway where cholesterol can contribute to an imbalance. When cholesterol moves through the blood to individual cells, it can travel in groups such as lipoproteins, which also contain fats and proteins. When the cholesterol is moving through your blood in Low Density Lipoproteins (LDL) it can undergo oxidation by free radicals in the artery walls. Some medical experts theorize that the oxidized LDL cholesterol becomes trapped in the artery walls as imbalanced deposits instead of completing the journey to join cell membranes. These deposits can eventually reduce the size and function of the arteries, compromising blood flow. Thus, antioxidant protection, balanced triglyceride production, and normal cholesterol production by the liver can all be critically important to your good health. And SYTRINOL™ provides all of these benefits.

How SYTRINOL™ Supports Heart Health

SYTRINOL is a powerful scientifically formulated blend protected by U.S. patent numbers 6,251,400, 09/ 481724. It contains natural citrus polymethoxylated flavones (PMFs) and tocotrienols that go deep to address the root causes of cholesterol wellness.

Citrus PMFs

Polymethoxylated flavones are types of polyphenolic compounds called flavonoids, which are the largest known category of phytonutrients. Health benefits of various flavonoids include antioxidant activity, immune system support, and cellular protection. The unique structure of polymethoxylated flavones, which naturally contain methyl groups paired with oxygen in key places, enables PMFs to interfere with cholesterol production. The citrus PMFs in SYTRINOL, such as tangeretin and sinensetin, promote normal cholesterol levels by inhibiting both the production of cholesterol precursors, such as cholesteryl esters, and the activity of HMG CoA Reductase, an enzyme that synthesizes cholesterol in the liver. These PMFs can also balance the body’s production of triglycerides by inhibiting the activity of your liver’s triglyceride producing enzyme, diacylglycerol acetyltransferase. Since LDL cholesterol is made from cholesterol and triglycerides, decreasing your liver’s production of triglycerides will reduce the amount of those triglycerides available to form LDL cholesterol compounds.

Tocotrienols

Tocotrienols are compounds similar to vitamin E in structure and function. The tocotrienols in SYTRINOL increase degradation of cholesterol building blocks such as Apolipoprotein B, interfere with cholesterol production, and provide antioxidant protection. The tocotrienols in SYTRINOL are also especially protective antioxidants for LDL cholesterol compounds that have already been produced, helping to prevent the oxidized LDL cholesterol conditions that may affect your cardiovascular circulation.

SYTRINOL’s Proactive Synergy

SYTRINOL works so well because this natural blend of PMFs and tocotrienols works proactively, synergistically, and independently. In preliminary human research, SYTRINOL proactively supported balanced cholesterol and triglyceride production by the liver through the synergistic effects of the PMFs and tocotrienols. Furthermore, SYTRINOL promotes LDL cholesterol antioxidant protection.

The above information has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Other products work reactively to disable existing cholesterol and may only work in conjunction with diets. And because SYTRINOL works independently of diet, you can take it anytime.

Three Lifestyle Strategies for Cardiovascular Health

1. Exercise regularly to increase hearthealthy HDL cholesterol and lower blood triglycerides (fats).

2. Eat a healthy diet rich in fruits, vegetables, whole grains, and lean proteins to help maintain normal cholesterol and triglyceride levels.

3. Take the right supplements to promote your cardiovascular health. In preliminary clinical studies, the amino acid L-ARGININE supported healthy blood flow to the heart and body. GARLIC OIL helps to maintain healthy cholesterol levels and promotes healthy circulation. POLICOSANOL CHOLESTEROL COMPLEX, CHOLESRESPONSE™, CHOLESFIBER™, CHOLESTREX®, and GRAPEFRUIT PECTIN all help to support normal cholesterol levels. HEART RESPONSE™ and HEART SCIENCE™ are advanced formulas that address heart health. Additionally, you can get cardiovascular system supporting compounds such as folic acid, betacarotene, CoQ10, lipoic acid, ginkgo, grapeseed extract, hawthorn extract, magnesium, vitamin E, and many other nutrients in LIFE FORCE MULTIPLE™, Source Naturals’ best-selling multiple. There is a revolution underway in natural health consciousness, and your local health food store is at the forefront. You can benefit right now – long before word spreads to the general public – with the innovative heart nutrition of SYTRINOL, a CHOLESTEROL RESCUE™ product. SYTRINOL™ is a trademark of KGK Synergize exclusively licensed worldwide to SourceOne Global Partners.

References
Guthrie, N. and Kurowska, E.M. (2000). Anticancer and Cholesterol-Lowering Activities of Citrus Flavonoids. Handbook of Nutraceuticals and Functional Foods, Wildman, R.E.C, Ed., CRC Press, Boca Raton, FL, 113-126. Guthrie, N. and Kurowska, E.M. (2000). Anticancer and Cholesterol-Lowering Activities of Tocotrienols. Handbook of Nutraceuticals and Functional Foods, Wildman, R.E.C, Ed., CRC Press, Boca Raton, FL, 269-280.

--
Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=516)

Date: June 24, 2005 05:45 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Source Naturals Goes Skin Side Out

Source Naturals® Goes Skin Side Out

Affordable Skin Care Line with Scientifically Advanced Nutraceuticals

Scotts Valley, California - May 28, 2003 - Source Naturals®, creators of the highly-acclaimed line of health and wellness supplements, has released a new natural cosmetic line intended to enhance healthy skin through formulations using the latest breakthrough skincare ingredients. The all-natural Skin Eternal™ line includes products that address skin health both internally and externally.

Skin Eternal™ Cream

Skin Eternal™ Serum

Skin Eternal™ DMAE Serum

Skin Eternal™ Bath Oil

Skin Eternal™ Tablets

Skin Eternal™ Plus Tablets

Skin Eternal™ HA Tablets

People react enthusiastically when they learn that they can get these powerful new skin-care products with all the proven, scientifically advanced ingredients at a fraction of the cost of similar products on the market," said LaVonne Whitley, Marketing Director at Source Naturals. Additionally, people are confident that Source Naturals conducts thorough research, selecting only the finest natural ingredients. We are proud to enter the self-care cosmetic arena with such strong products!"

Skin Eternal Cream is thick and rich for use primarily on the face. It is gentle and effective on targeted areas such as under the eyes and on the neck. This cream is formulated using a completely unique blend of natural oils, nutrients and plant extracts including: alpha lipoic acid; biotin; CoQ10; DMAE; jojoba oil; squalene; tocotrienols; vitamin C-ester. Available in 2 oz. and 4 oz. sizes.

Skin Eternal Serum is an aqueous moisturizing serum for hydrating and replenishing the complexion. The serum is easily absorbed, and immediately softens the skin. This product contains a powerful blend of nutrients and plant extracts which deeply penetrate the skin. These include: aloe vera; alpha lipoic acid; biotin; CoQ10; DMAE; MSM; as well as vitamins A, C-ester, D-3, and E. Available in 1 and 1.7 oz. sizes.

Skin Eternal DMAE Serum is targeted for mature skin, providing a higher concentration of DMAE to give skin a radiant, healthy look. Available in 1 and 1.7 oz. sizes.

Skin Eternal Bath Oil seals in moisture, and provides strong protection by adding nutrients to the skin's hydrolipic film. This special formulation includes alpha lipoic acid; DMAE; vitamins C-ester and E; along with a rich blend of other nutrients and plant extracts. Available in 4, 8 and 16 oz. sizes.

All Skin Eternal topical products are hypoallergenic and therefore are effective on even delicate and sensitive skin. None of the finished products have been tested on animals.

Skin Eternal Tablets provide key nutraceuticals that support body systems involved with healthy, radiant skin. These include alpha lipoic acid; DMAE; vitamins C-ester and E; and grapeseed extract. These important ingredients also provide added protection against free radical damage. Available in 60, 120 and 240 count bottles.

Skin Eternal Plus is a Bio-Aligned Formula™ that includes the same important nutraceuticals found in Skin Eternal Tablets, plus 30 more! This formula is designed to deeply address skin imbalances. This Bio-Aligned Formula supports multiple body systems involved in skin health, including: antioxidant defense, cell renewal, connective tissues and cell membranes, blood and liver cleansing, and muscle and nerve functions. Available in 30, 60 and 120 count bottles.

Skin Eternal HA Tablets are a rich source of hyaluronic acid, which helps maintain and regulate the water balance of tissues, keeping skin soft and moisturized. Hyaluronic acid also facilitates the transport of nutrients and waste, promoting deeply healthy and radiant skin. The product will be launched under the Skin Eternal label this summer and will be available in 30, 60 and 120 count bottles.

--
Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=424)

Date: June 12, 2005 05:53 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Acupuncture nutrient Connection

Acupuncture nutrient Connection by Robert Gluck Energy Times, November 1, 1998

The theory behind the practice of acupuncture confounds western science. This therapy, originating in Asia, is based on the concept that currents of energy called meridians flow through your body. However, no one has ever been able to conclusively demonstrate the existence of these meridians.

Despite the evasiveness of these energy streams, Traditional Chinese Medicine (TCM) holds that alterations in these energy flows can disrupt health and cause pain. Consequently, an acupuncturist punctures your skin with specialized needles to redirect the body's vital energy.

Alleviating Illness

Despite the fact that western scientists have not been able to find satisfactory evidence of the existence of these energetic meridians, studies show that acupuncture works and is especially effective at relieving pain. This therapy has been used to alleviate a variety of conditions including chronic pain, nausea and even mental illness. In addition, some practitioners apply it to those trying to shake off the chains of drug addiction. (More recently, many practitioners now also successfully use acupuncture to relieve physical problems in animals.)

Of course, no matter what your perspective on this therapy, acupuncture's no panacea. While you might use acupuncture to relieve the discomforts of chemotherapy, you wouldn't use this technique as your primary weapon against a dangerous disease like cancer. Still, this reliable therapy occupies a welcome spot as an adjunct to many mainstream therapies. Consequently, many mainstream practitioners accept the validity of using acupuncture and many managed care companies reimburse this therapy. Some HMOs even keep a list of approved acupuncturists that they make available to enrollees.

Acupuncture East and West

The practice of acupuncture dates back at least 2200 years ago in Asia. Only during the last forty years has it become well-known and widely available in the United States. Today, 29 accredited acupuncture schools train practitioners in North America. In addition, traditional healers in Belize (south of Mexico) have been found to use a form of acupuncture derived from traditional Mayan medicine.

Is the use of acupuncture by Mayan shamans coincidence? Or further evidence that acupuncture meridians really exist? No one knows for sure, although some experts believe the Mayan use of this therapy supports the notion that the original ancestors of the Mayans migrated from Asia.

Needle Relief

Acupuncturists insert needles into the body to relieve pain or enhance bodily functions. TCM holds that acupuncture, and the manipulation of these tiny needles, moves and manipulates qi (pronounced chee), the body's energy force.

"Acupuncture is a method of balancing the body's energy," says Carol Alexander, an acupuncturist at the North Jersey Health and Pain Relief Center in Hackettstown, New Jersey. "Disease occurs because of an imbalance...Insertion of the acupuncture needles into meridians will bring about the balance of qi." Alexander has practiced acupuncture for 10 years and studied at the Tri-State School of Traditional Acupuncture in Stanford Connecticut.

Alexander says patients sometimes suffer a blockage of qi or display too much or too little qi. The manipulation and placement of the acupuncture needles vary according to the need for adjusting meridian energy flow.

Acupuncture can be used to prevent disease and, if disease is already rampant, it can be used to help the body correct the problem.

In conjunction with her use of acupuncture needles, Alexander rarely prescribes single herbs but uses combinations of whole herbs that are very specific for different diseases and disease patterns. "Certain herbs, such as ginseng, are very prized in Chinese medicine," Alexander notes.

"Astragalus is an herb used in China and around the world to tonify the qi and increase qi energy as well as stimulate the immune system."

Licorice Root

Alexander uses licorice root for assisting digestion and for helping women with menopausal discomforts. On the other hand, she recommends whole food concentrates like bee pollen granules for enhancing the immune system, peppermint for treating gastro-intestinal problems plus fiber supplements as well as the antioxidant/antihistamine quercetin, coenzyme Q10 and melatonin.

"In terms of classes of nutrients, I use a lot of whole food concentrates: the green concentrates like barley greens, wheat grass powder, spirulina and blue-green algae," Alexander says. "These are high in minerals, antioxidants, nutrients and fatty acids. I also use some soy products because the isoflavone concentrates are very much anti-cancer."

The Fine Points of Acupuncture

Acupuncture needles are very fine, as thin as hairs. They are available in a variety of diameters and lengths. When an acupuncturist inserts these needles, the sensation is that of mild pinpricks. (The needles enter the body at depths of only 1/8th inch to two inches.) In many cases people experience mild pleasure during needle manipulation.

"From a Western point of view it's important to explain that there is a distinct function of acupuncture treatment and that is to increase circulation," Alexander says. "We do stimulate nerves and we know that with the stimulation of nerves many neurochemicals and neurotransmitters are released. They move through the nerves and find receptor sights, some in the brain, some in other parts of the body."

By stimulating nerves, acupuncturists can calm inflammation and deaden pain. These effects are believed to be linked to the release of endorphins and dinorphins, powerful painkillers and anti-inflammatories that the body produces for itself. Most acupuncturists use this therapy as part of an overall, multi-faceted treatment plan.

Unique Energy

"Qi is what makes you different from a sack of chemicals," points out David Molony, an acupuncturist at the Lehigh Valley Acupuncture Center in Catasaqua, Pennsylvania who studied at the Nanjing Traditional Medicine Hospital in China and has lectured at Cornell University.

What You Need

"You can manipulate qi with acupuncture, herbs and diet. Because people's bodies work differently, there are different approaches. When you ask the question what nutrients and herbs are effective at enhancing acupuncture, it depends on what the person needs, according to an Oriental Medicine diagnosis."

An Oriental Medical examination, Molony says, begins with a long list of health questions designed to reveal factors that contribute to disease. A practitioner measures your pulse in several different places along your arm, inspects your tongue, may press on your stomach, sniff your general odor and closely examine your nails and skin for signs of problems.

"You take in everything you can," adds Molony, a board member of the Acupuncture Society of Pennsylvania and former board member of the American Association of Acupuncture and Oriental Medicine. "This gives you clues that you need in order to make your diagnosis."

Acupuncturists use nutrients and herbs that complement the treatment, as well as dietary and lifestyle counseling. Some acupuncturists don't specialize in herbal remedies, so these practitioners might go to a specialist like David Winston for advice. Winston, an herb expert skilled in Cherokee, Chinese and Western eclectic herbal medicine, works as an instructor, lecturer and consultant.

"In China, acupuncture is considered a complementary therapy; you generally don't go for treatment and get purely acupuncture," says Winston who is working on a book about saw palmetto. "Herbal medicine, diet and qi gong are important therapies in their own right and acupuncture is one of those therapies. Qi gong is a form of martial arts that focuses on unique breathing and visualization methods. Qi is not exactly energy, it's energy in movement; it's what makes the blood move."

Open Blockages

Acupuncture is used to open blockages that sometimes build up in what TCM practitioners characterize as excessive heat or cold. These hot and cold spots do not always literally refer to the temperature of the body but are meant to depict changes in the character of the body's vital energy.

Chinese acupuncturists don't necessarily treat diseases, but target clusters of physical discomforts. Winston says, "Herbal formulas change depending on the 'symptom pictures.' Somebody could have acute appendicitis but the symptom picture could vary. Usually Chinese acupuncturists use herbs like isatis (a very cold, drying herb that's a powerful anti-bacterial agent) and coptis (a powerful anti-bacterial herb)."

Americans often visit acupuncturists complaining of back pain or some type of musculoskeletal problem-a wrenched knee, a ligament that hasn't healed properly or perhaps a torn rotator cuff. "If the injury is hot to the touch, it's red, it's inflammatory-that's a condition where there's excessive heat and in that condition the acupuncturist would give herbs that are cooling and anti-inflammatory such as the root of large leaf gentian."

Pain that Moves

If someone suffers pain that moves, pain that is sometimes exacerbated by damp or humid conditions, acupuncturists often prescribe clematis root, a wild variety of the garden plant that is an anti-spasmodic, or acanthopanax, a relative of Siberian ginseng used for damp pain.

"If there's pain with excessive dampness," Winston says, "acupuncturists might use duhuo, a drying herb that opens the meridians."

Molony agrees with Winston that when it comes to choosing herbs to enhance acupuncture, accurate analysis of the root cause of the health problem is paramount to making the right decisions. For example, if a person is qi deficient and her tongue is thickly coated, she may not be processing her energy properly. Phlegm builds up, decreasing energy. "What you want to do is give them herbs that move phlegm, like citrus peel, and combine that with acupuncture points that move phlegm also," Molony says.

For stimulating metabolism, Molony uses lactoferin-processed colostrum from cows. He uses ginseng and atractylodes as qi tonics and he adds herbs like magnolia bark or atractylodes alba.

Helpful Antioxidants

He believes antioxidants are helpful too, as preventive medicines, including vitamins C and E. These valuable nutrients disarm the harm that reactive molecules can wreak within the body.

So how important are herbs and nutrition to enhance acupuncture's effectiveness? Acupuncturists seem to agree that healthy doses of antioxidants (such as vitamins C and E plus antioxidants from grapeseed extract) as well as specialized herbs, turn this therapy into a highly effective healing tool. Those wanting to benefit from this penetrating technique should stock up on nutrients. Then sit back, relax, kick off your shoes and let the acupuncturist do her stuff.

--
Vitanet ®

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=314)

Date: June 06, 2005 08:45 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Skin Eternal - Replenish Your Skin

Skin Eternal

Source Naturals is proud to introduce our new SKIN ETERNAL Cosmetic Line. Our advanced skin care products recharge and revitalize your skin. Each product features scientifically advanced nutraceuticals: nutrients and botanicals with an inborn affinity for skin. You can nourish your skin with Source Naturals’ richly emollient SKIN ETERNAL CREAM smoothed under your eyes or on your neck. Or use our light, aqueous SKIN ETERNAL SERUM. Both products gently addresses imbalances and infuse skin with visible radiance. For a luxuriant, moisturizing bath, simply add SKIN ETERNAL BATH OIL under warm running water. Whatever your individual preference, Source Naturals has a SKIN ETERNAL product that will leave your skin looking refreshed and energized.

Now available from Source Naturals®: a variety of elegant cosmetics to moisturize, smooth and tone your skin.

Your skin is a reflection of your health and well-being. To attain skin that looks truly alive, energized and refreshed, we believe a holistic approach is necessary. This includes nourishing your body with fresh, organic foods, exercising every day to motivate your mind and spirit, and eliminating unhealthy lifestyle choices. As part of this holistic approach, the Skin Eternal™ cosmetic line feeds your skin cells with scientifically advanced nutraceuticals: nutrients and botanicals with an inborn affinity for skin.

SKIN ETERNAL™ CREAM

Apply this rich and luxurious blend under and around your eyes or massage it with upward strokes onto your neck—your skin will immediately feel the difference! SKIN ETERNAL CREAM features nutrients, natural oils and plant extracts. Included are alpha lipoic acid, biotin, CoQ10, DMAE, jojoba oil, MSM, squalane, tocotrienols, and vitamin C-ester, as well as extracts of grape seed, ginkgo, ginseng, green tea, sage, marigold, and grapefruit seed.

SKIN ETERNAL™ SERUM

SKIN ETERNAL SERUM is an aqueous moisturizing serum that contains a rich blend of nutrients and plant extracts. It is easily absorbed, and immediately makes skin feel softer and replenished. SKIN ETERNAL SERUM is lightly scented with pure lavender and lemon oils, and contains nutrients and herbs unavailable in other topical preparations. These include aloe vera, alpha lipoic acid, biotin, CoQ10, DMAE, MSM, vitamins A, C-ester, D-3 and E, and chamomile. Source Naturals also offers SKIN ETERNAL DMAE SERUM.

SKIN ETERNAL™ BATH OIL

OUR NEW SKIN ETERNAL BATH OIL adds to your skin’s hydrolipic film, lightly coating your skin with nutrients. It holds moisture inside and protects your skin. Its unique formula is rich in alpha lipoic acid, DMAE, essential fatty acids, vitamins C-ester and E, plus other nutrients and plant extracts. SKIN ETERNAL BATH OIL is lightly scented with pure lavender and lemon oils. And it is hypoallergenic and contains no alpha hydroxy acids—so it can be used even on delicate, sensitive skin.

Lifestyle Tips for Healthy Skin: A Strategy for WellnessSM

Eat a Healthy Diet Low-nutrient foods, such as sugar and refined carbohydrates, will not provide the vitamins and minerals your skin needs. Choose unprocessed organic foods, high in antioxidants such as beta carotene (carrots, apricots, and squash), vitamin C (oranges and peppers), vitamin E (cold-pressed oils, nuts and seeds), selenium (tuna, garlic, onions and broccoli) and zinc (whole grains, most seafood, and onions). Essential fatty acids, such as those in oily fish, flaxseed and olive oil, are important for skin repair. Eat high-fiber fruits, vegetables, whole grain bread and cereals, and brown rice. Restrict excess sodium intake.

Take Supplements

Key nutraceuticals can help radiate beauty from within, by supporting body systems involved with healthy, radiant skin. These nutraceuticals include alpha lipoic acid, DMAE, ascorbyl palmitate (vitamin C-ester), vitamin E and grapeseed extract. Source Naturals offers you SKIN ETERNAL™ tablets with these five ingredients, to protect against free radical damage and provide cofactors for healthy skin tissue. Source Naturals SKIN ETERNAL PLUS is a Bio-Aligned Formula™, which includes these key nutraceuticals plus 30 more! It is designed to support multiple body systems: antioxidant defense, connective tissue, cell membranes, cell renewal, blood and liver cleansing, muscle and nerve function, and stress response. It is also useful to supplement with essential fatty acids, such as omega-3 and omega-6 fatty acids, flaxseed and primrose oil.

Drink Water

Our bodies are made up of 50-70% water, so it’s important to drink at least 1.5 liters daily. Water flushes out wastes, and acts as an internal moisturizer, keeping skin hydrated and supple. Spring water is beneficial since it contains trace minerals vital to healthy skin.

Protect Your Skin from the Sun

Avoid direct sun from 10 am to 4 pm, when ultraviolet radiation is strongest. Use sunscreen even during winter and on cloudy days. Wear a broad-brimmed hat and sunglasses with full UV protection.

Get Plenty of Sleep

Research has shown that skin regenerates itself between 1-3 am; lack of sleep during those hours can cause skin to look dull or puffy. Taking a melatonin supplement can be helpful in supporting your body’s normal sleep cycle.

Exercise Regularly

Exercise increases circulation, which delivers nutrients necessary for a clear, glowing complexion. It also burns off fat, helps eliminate toxins, and is a great stress reliever. Exercise three to five times a week until you are perspiring freely and breathing deeply.

Avoid Excessive Alcohol and Coffee

Alcohol weakens the immune system and depletes nutrients. It causes dehydration, depriving skin of moisture, and overtaxes the liver, which helps keep impurities from reaching other organs. Alcohol consumption can lead to broken or distended capillaries, especially over the nose and cheeks. Caffeine-rich beverages like coffee promote dehydration, leaving skin flaky and dry. Substitute herbal or green tea for coffee.

Stop Smoking

Smoking slows healing and regeneration, causes carbon monoxide to increase in blood, and induces free radical formation. Nicotine constricts blood vessels and reduces blood flow to skin. The benzopyrene in cigarette smoke inhibits absorption of vitamin C, which is important for collagen synthesis.

--
VitaNEt ®
VitaNet ® Staff

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=195)